Martin Corry, Lewis Moody, George Chuter and Andy Goode return from England duty, with Corry captaining the side from no.8.
Martin Castrogiovanni and Marcos Ayerza regain their places following their exploits with Italy and Argentina respectively, as they complete an all international front row.
Geordan Murphy is the seventh returning international to be named in the Tigers side. The Irishman takes his place on the right-wing, with Sam Vesty at full back and Tom Varndell at no.11.
Harry Ellis partners Goode at half-back, with Dan Hipkiss named alongside Daryl Gibson in the centre.
Leo Cullen and Louis Deacon get the nod in the second row, with a further two internationals named on the bench in Alex Moreno and new-Scottish cap James Hamilton.
Tigers
15 Sam Vesty
14 Geordan Murphy
13 Dan Hipkiss
12 Daryl Gibson
11 Tom Varndell
10 Andy Goode
9 Harry Ellis
1 Marcos Ayerza
2 George Chuter
3 Martin Castrogiovanni
4 Leo Cullen
5 Louis Deacon
6 Lewis Moody
7 Shane Jennings
8 Martin Corry (captain)
Replacements
16 James Buckland
17 Alex Moreno
18 James Hamilton
19 Brett Deacon
20 Scott Bemand
21 Matt Cornwell
22 Johne Murphy
