Adams Park, home of London Wasps, hosts the match, and while a win for Ireland would secure a Grand Slam, England could secure a second successive Championship win with a victory of their own.
Kick-off is at 8.05pm on Friday and the game is to be shown live on Sky Sports HD 2.
England Under-20 (v Ireland, Friday)
15 Anthony Watson (London Irish)
14 Marland Yarde (London Irish)
13 Will Addison (Sale Sharks)
12 Ryan Mills (Gloucester Rugby)
11 Charlie Walker (Harlequins)
10 Tom Heathcote (Bath Rugby)
9 Dan Robson (Gloucester Rugby)
1 Alec Hepburn (London Wasps)
2 Koree Britton (Gloucester Rugby)
3 Kyle Sinckler (Harlequins)
4 Tom Price (Leicester Tigers)
5 Dom Barrow (Leeds Carnegie)
6 Matt Kvesic (Worcester Warriors)
7 Chris Walker (Leeds Carnegie) (C)
8 Jack Clifford (Harlequins)
Replacements
16 Nathan Morris (London Wasps)
17 Luke Cowan-Dickie (Exeter Chiefs)
18 Ross Harrison (Sale Sharks)
19 George Merrick (Harlequins)
20 David Sisi (London Irish)
21 Ben Spencer (Saracens)
22 Sam Hill (Exeter Chiefs)
23 Ben Ransom (Saracens)
