Fijian wing Goneva, scorer of two tries in the final pre-season fixture against Nottingham last weekend, makes his first Premiership appearance after a summer move from Tarbes in France, while South African second-row Andrew also runs out for the first time in the competition.
Geordan Murphy, beginning his 16th season as a Leicester Tiger, leads the team out as captain.
Micky Young partners Toby Flood at half-back, and Logovi’i Muliola and Tom Youngs join Dan Cole in the starting front row.
Brett Deacon, who returned to his hometown club in the summer after two seasons with Gloucester, is named among the replacements. Jordan Crane, who missed the entire 2010/11 season with a knee injury, makes his return to the matchday squad.
Tigers director of rugby Richard Cockerill said: “London Welsh fought hard to get into the Aviva Premiership and it will be a big occasion for them in their first Premiership game. There is a lot of experience in their squad and their coaching team.
“We’ve got to be accurate in what we do for the whole game. We’ve got some good competition for places in the squad, we’ve given them all valuable game-time in the pre-season, but this is where it really matters.”
LEICESTER TIGERS (v London Welsh, Kassam Stadium, Sunday 2pm)
15 Geordan Murphy (c)
14 Scott Hamilton
13 Manusamoa Tuilagi
12 Anthony Allen
11 Vereniki Goneva
10 Toby Flood
9 Micky Young
1 Logovi’i Mulipola
2 Tom Youngs
3 Dan Cole
4 Rob Andrew
5 Geoff Parling
6 Steve Mafi
7 Julian Salvi
8 Thomas Waldrom
Replacements
16 George Chuter
17 Boris Stankovich
18 Martin Castrogiovanni
19 Brett Deacon
20 Jordan Crane
21 Sam Harrison
22 George Ford
23 Matt Smith
London Welsh: 15 Tom Arscott, 14 Phil MacKenzie, 13 Sonny Parker, 12 Hudson Tonga’uiha, 11 Joe Ajuwa, 10 Gordon Ross, 9 Jonah Holmes; 1 Franck Montanella, 2 Neil Briggs, 3 Paulica Ion, 4 Jonathan Mills (c)©, 5. Kirill Kulemin, 6 Ed Williamson, 7 Lee Beach, 8 Daniel Browne.
Replacements: 16 Greg Bateman, 17 Tom Bristow, 18 Arthur Joly, 19 Martin Purdy, 20 Alfie To’oala, 21 Nick Runciman, 22 Seb Jewell, 23 Nick Scott
