Ireland international Murphy has made more than 300 appearances for Tigers since his debut in 1997, scoring 93 tries.
Scott Hamilton is in line for his 100th starting appearance in a backline showing just one change from last week’s victory at London Welsh as Sam Harrison steps in for the injured Micky Young at scrum-half. Vereniki Goneva makes his first appearance in a competitive fixture at Welford Road following his summer move from Tarbes in France.
In the forward pack there is a recall for props Boris Stankovich and Martin Castrogiovanni, and second-row Graham Kitchener for their first starts of the season.
Australian scrum-half Pat Phibbs is called up to the matchday squad following Young’s ankle injury.
“Worcester were very much up for the battle against Bath last weekend and we expect another tough contest,” said Tigers director of rugby Richard Cockerill. “We have to be accurate in what we are doing. Whenever we made mistakes against London Welsh it cost us and that is a warning.”
Leicester Tigers (v Worcester Warriors, Welford Road, Saturday 3pm)
15 Geordan Murphy (c)
14 Scott Hamilton
13 Manusamoa Tuilagi
12 Anthony Allen
11 Vereniki Goneva
10 Toby Flood
9 Sam Harrison
1 Boris Stankovich
2 Tom Youngs
3 Martin Castrogiovanni
4 Graham Kitchener
5 Geoff Parling
6 Steve Mafi
7 Julian Salvi
8 Thomas Waldrom
Replacements
16 Rob Hawkins
17 Logovi’i Mulipola
18 Dan Cole
19 Rob Andrew
20 Jordan Crane
21 Pat Phibbs
22 George Ford
23 Matt Smith
Worcester Warriors
15 Chris Pennell
14 Josh Drauniniu
13 Alex Grove
12 Josh Matavesi
11 David Lemi
10 Andy Goode
9 Shaun Perry
1 Matt Mullan
2 Aleki Lutui
3 John Andress
4 James Percival
5 Dean Schofield (c)
6 Chris Jones
7 Sam Betty
8 Semisi Taulava
Replacements
16 Ollie Hayes
17 Ceri Jones
18 James Currie
19 Craig Gillies
20 Matt Kvesic
21 Jonny Arr
22 Joe Carlisle
23 Ben Howard
