The teenagers line up side by side in the Tigers midfield in a team that includes their Development squad colleagues Joe Cain and Harry Thacker who made their senior bows in the Anglo-Welsh competition last season.
Italy Under-20 prop Tiziano Pasquali and Academy full-back Perry Humphreys are among the replacements in their first appearance in a senior matchday squad.
Miles Benjamin makes his first senior appearance at Welford Road since joining the club last summer and Owen Williams continues at fly-half.
Experience in the team is provided by skipper Boris Stankovich, back-rowers Jamie Gibson and Thomas Waldrom, and Scott Hamilton in the backline. George Chuter and David Mélé are also among the replacements.
The bench also includes Tom Price, Harry Wells and Henry Purdy who were all part of the victorious England Under-20s squad at this summer’s World Junior Championships.
Terrence Hepetema, Matt Smith and Dan Bowden were injured during last Saturday’s game against Harlequins and sit out this week.
Also unavailable due to injury are Anthony Allen, Gonzalo Camacho, Tom Croft, Vereniki Goneva, Rob Hawkins, Ryan Lamb, Scott Steele, Mathew Tait and Manu Tuilagi.
Tigers have five players away with England, plus Marcos Ayerza and Pablo Matera with Argentina and Logovi’i Mulipola (Samoa) this weekend.
All home games in the pool stages of the LV= Cup are included in Tigers season tickets.
Tickets for the game are available from the Tigers ticket office. Phone 0844 856 1880 or call in at Welford Road (open until 5pm Thursday and from 9am Friday) or book online at www.leicestertigers.com
Leicester Tigers (v Ospreys, Welford Road, Friday 7.45pm)
15 Scott Hamilton
14 Blaine Scully
13 George Catchpole
12 Javiah Pohe
11 Miles Benjamin
10 Owen Williams
9 Sam Harrison
1 Boris Stankovich (c)
2 Harry Thacker
3 Fraser Balmain
4 Joe Cain
5 Sebastian de Chaves
6 Michael Noone
7 Jamie Gibson
8 Thomas Waldrom
Replacements
16 George Chuter
17 Tom Bristow
18 Tiziano Pasquali
19 Tom Price
20 Harry Wells
21 David Mélé
22 Perry Humphreys
23 Henry Purdy
Ospreys
15 Ross Jones
14 Hanno Dirksen
13 Tom Isaacs
12 Matthew Jenkins
11 Tom Grabham
10 Sam Davies
9 Tom Habberfield
1 Marc Thomas
2 Matthew Dwyer
3 Joe Rees
4 Lloyd Peers (c)
5 Rhodri Hughes
6 Graham Knoop
7 Arthur Ellis
8 Morgan Allen
Replacements
16 Rhys Hutcherson
17 Nicky Smith
18 Dan Suter
19 Sam Williams
20 Jack Jones
21 Jake Cole
22 Nathan Edwards
23 Aisea Natoga
