The 32-man England squad includes Dan Cole, Tom Croft, Louis Deacon, Toby Flood, Manu Tuilagi and Ben Youngs.
They will be joined by Tigers second-rower Parling who is one of four players elevated to the squad as temporary injury cover.
Leicester Tigers director of rugby Richard Cockerill said: “We congratulate all of our players who have been chosen as part of the new England squads.
“It is particularly gratifying for the club to see that five of the six in the senior squad have come all the way through the ranks at Leicester Tigers, from the Academy up to establishing themselves in the first-team squad here and on into Test rugby with England.
“This club always retains a strong home-grown core and it says a lot for the strength of our set-up that they go all the way to international status.”
There are 15 changes to the August 2011 squad, including first time call-ups for Brad Barritt, Owen Farrell, Lee Dickson, Calum Clark and Ben Morgan. Flood, with 46 international caps, is the most experienced player in the squad.
Dave Attwood, Alex Goode and Henry Trinder join Parling as temporary replacements for injury victims Courtney Lawes, Flood, Deacon and Tuilagi.
The Elite Saxons squad includes Tigers players Thomas Waldrom, Anthony Allen, Billy Twelvetrees and Micky Young.
ENGLAND ELITE PLAYER SQUAD
Forwards
Mouritz Botha (Saracens)
Calum Clark (Northampton Saints)
Alex Corbisiero (London Irish)
Dan Cole (Leicester Tigers)
Tom Croft (Leicester Tigers)
Louis Deacon (Leicester Tigers)
Phil Dowson (Northampton Saints)
Dylan Hartley (Northampton Saints)
Courtney Lawes (Northampton Saints)
Joe Marler (Harlequins)
Lee Mears (Bath Rugby)
Ben Morgan (Scarlets)
Tom Palmer (Stade Francais)
Chris Robshaw (Harlequins)
Matt Stevens (Saracens)
Rob Webber (London Wasps)
David Wilson (Bath Rugby)
Tom Wood (Northampton Saints)
Backs
Chris Ashton (Northampton Saints)
Brad Barritt (Saracens)
Mike Brown (Harlequins)
Lee Dickson (Northampton Saints)
Owen Farrell (Saracens)
Toby Flood (Leicester Tigers)
Ben Foden (Northampton Saints)
Charlie Hodgson (Saracens)
Joe Simpson (London Wasps)
Charlie Sharples (Gloucester Rugby)
David Strettle (Saracens)
Manusamoa Tuilagi (Leicester Tigers)
Jordan Turner-Hall (Harlequins)
Ben Youngs (Leicester Tigers)
ENGLAND SAXONS EPS
Forwards
David Attwood (Bath Rugby)
Chris Brooker (Harlequins)
Paul Doran Jones (Northampton Saints)
Matt Garvey (London Irish)
James Gaskell (Sale Sharks)
Jamie Gibson (London Irish)
Joe Gray (Harlequins)
Tom Johnson (Exeter Chiefs)
Joe Launchbury (London Wasps)
Matt Mullan (Worcester Warriors)
Luke Narraway (Gloucester Rugby)
David Paice (London Irish)
Geoff Parling (Leicester Tigers)
George Robson (Harlequins)
Andrew Saull (Saracens)
Henry Thomas (Sale Sharks)
Thomas Waldrom (Leicester Tigers)
Nick Wood (Gloucester Rugby)
Backs
Nick Abendanon (Bath Rugby)
Anthony Allen (Leicester Tigers)
Delon Armitage (London Irish)
Matt Banahan (Bath Rugby)
Freddie Burns (Gloucester Rugby)
Karl Dickson (Harlequins)
Alex Goode (Saracens)
Jonathan Joseph (London Irish)
Ryan Lamb (Northampton Saints)
Jonny May (Gloucester Rugby)
Ugo Monye (Harlequins)
Henry Trinder (Gloucester Rugby)
Billy Twelvetrees (Leicester Tigers)
Micky Young (Leicester Tigers)
