Ben Youngs will make his 100th appearance for England in Saturday’s Guinness Six Nations match against Italy in Rome.
The Leicester Tigers scrum-half is already the second most-capped England men’s player of all time after Jason Leonard (114 caps) and will become only the second to reach a century of caps.
He made his Test debut against Scotland in March 2010 as a replacement and reaches 100 in the re-arranged final round of the 2020 Six Nations this weekend.
There is also a milestone for hooker Jamie George, who will make his 50th appearance.
England need a bonus-point win at the Stadio Olimpico to be contention for the Championship title depending on the result in France versus Ireland, which follows the game in Rome.
Tigers prop Ellis Genge is named on the bench for the trip to Rome.
Head coach Eddie Jones said: “We will celebrate two major achievements in Ben Youngs and Jamie George’s milestones. It’s testimony to their skill, hard work and love of playing for England, and there is more to come from both of them.”
Italy v England is live on ITV 1 and BBC Radio 5 Live.
England (v Italy, away, Saturday 4.45pm UK time)
15 George Furbank (Northampton Saints, 2 caps)
14 Anthony Watson (Bath Rugby, 43 caps)
13 Jonathan Joseph (Bath Rugby, 50 caps)
12 Henry Slade (Exeter Chiefs, 29 caps)
11 Jonny May (Gloucester Rugby, 56 caps)
10 Owen Farrell (Saracens, 83 caps)
9 Ben Youngs (Leicester Tigers, 99 caps)
1 Mako Vunipola (Saracens, 59 caps)
2 Jamie George (Saracens, 49 caps)
3 Kyle Sinckler (Bristol Bears, 35 caps)
4 Maro Itoje (Saracens, 38 caps)
5 Jonny Hill (Exeter Chiefs, uncapped)
6 Tom Curry (Sale Sharks, 23 caps)
7 Sam Underhill (Bath Rugby, 18 caps)
8 Billy Vunipola (Saracens, 51 caps)
16 Tom Dunn, (Bath Rugby, uncapped)
17 Ellis Genge (Leicester Tigers, 18 caps)
18 Will Stuart (Bath Rugby, 3 caps)
19 Charlie Ewels (Bath Rugby, 15 caps)
20 Ben Earl (Bristol Bears, 3 caps)
21 Dan Robson (Wasps, 2 caps)
22 Ollie Lawrence (Worcester Warriors, uncapped)
23 Ollie Thorley (Gloucester Rugby, uncapped)
Italy: to come