Jerry Flannery returns to the front row, Jamie Heaslip comes in at No8 and Tomas O'Leary is named at scrum-half in the three changes since the win over Scotland.
Ireland Team (v Wales, Saturday 5.30pm)
15 Robert Kearney (UCD, Leinster)
14 Tommy Bowe (Ospreys)
13 Brian O'Driscoll (UCD, Leinster, captain)
12 Gordon D'Arcy (Lansdowne, Leinster)
11 Luke Fitzgerald (Blackrock College, Leinster)
10 Ronan O'Gara (Cork Constitution, Munster)
9 Tomas O'Leary (Dolphin, Munster)
1 Marcus Horan (Shannon, Munster)
2 Jerry Flannery (Shannon, Munster)
3 John Hayes (Bruff, Munster)
4 Donncha O'Callaghan (Cork Constitution, Munster)
5 Paul O'Connell (Young Munster, Munster)
6 Stephen Ferris (Dungannon, Ulster)
7 David Wallace (Garryowen, Munster)
8 Jamie Heaslip (Naas, Leinster)
Replacements
16 Rory Best (Banbridge, Ulster)
17 Tom Court (Malone, Ulster)
18 Mick O'Driscoll (Cork Constitution, Munster)
19 Denis Leamy (Cork Constitution, Munster)
20 Peter Stringer (Shannon, Munster)
21 Paddy Wallace (Ballymena, Ulster)
22 Geordan Murphy (Leicester Tigers)
