Three Leicester Tigers players were involved as the Guinness Women's Six Nations came to Mattioli Woods Welford Road.
Tigers HQ set the stage for England and Scotland, with the Roses bringing the fireworks.
England scored 42 unanswered points as part of a dominant first half, opening the scoring in the opening couple of minutes through Kelsey Clifford before hitting five more tries before the break.
Meg Jones and Francesca McGhie started on either side, with the former threading passes around, while McGhie beat a couple of defenders but couldn't break the deadlock against a relentless Red Roses resistance.
Scotland were much improved in the second period, with Leah Bartlett subbed on just before the hour mark.
The prop helping the visitors steady the scrum and adding her power to a rolling maul that rumbled over in the corner, giving Scotland their only score of the match.
In the end, however, England were just too far ahead for the visitors to think about a comeback and a late brace from Abby Dow saw the match finish 59 - 7.
More than 23,000 tickets have been sold for next Saturday's Gallagher Premiership fixture at Mattioli Woods Welford Road which doubles as this season's JTC Takeover Day.
Spaces at the crucial clash with Harlequins are filling up fast. Make The Obvious Choice and get your ticket sorted now before it's too late.
