Blaine Scully and the USA Eagles head home for the second leg of their Rugby World Cup play-off against Uruguay next weekend with honours even after a 27-27 draw in Montevideo on Saturday.
Leicester Tigers wing Scully gained his 16th Test cap for the Eagles as they came from 19-6 down in the first half to lead with three second-half tries but then saw their hosts clinch a late levelling score.
Tries came from hooker Phil Thiel, Northampton Saints forward Samu Manoa and Saracens full-back Wyles, with centre Folau Niua kicking three penalties and a conversion.
The Eagles had to survive a scare with 14 men when Uruguay scored a late try, confirmed by the television match official, but missed a potential match-winning conversion from a tight angle.
The second leg is next Saturday at Fifth Third Bank Stadium at Kennesaw State University, Atlanta. Victory would guarantee a place in the IRB Rugby World Cup 2015 in England, while a defeat would push them into the Repechage play-off.
USA Eagles: 15 Chris Wyles, 14 Blaine Scully, 13 Folau Niua, 12 Andrew Suniula, 11 Tim Maupin, 10 Toby L'Estrange, 9 Mike Petri; 1 Olive Kilifi, 2 Phil Thiel, 3 Eric Fry, 4 Hayden Smith, 5 Samu Manoa, 6 Todd Clever (c), 7 Scott LaValla, 8 Cam Dolan. Replacements: 16 Tom Coolican, 17 Nick Wallace, 18 Titi Lamositele, 19 Louis Stanfill, 20 Kyle Sumsion, 21 Shalom Suniula, 22 Seamus Kelly, 23 Luke Hume