With Tigers facing a league match just three days after defeat in the EDF Energy Cup Final and four days before a home date with Bristol Rugby, head coach Marcelo Loffreda rings the changes.
Kay is named as captain, while England Under-20 international Ollie Dodge makes his league debut on the wing after gaining senior experience with Bedford this season.
Tom Varndell, Christophe Laussucq, Sam Vesty, Benjamin Kayser, Julian White, Richard Blaze and Tom Croft all step up after being named among the replacements at Twickenham on Saturday, while Ayoola Erinle, Matt Cornwell and Ian Humphreys return to the backline.
Club captain Martin Corry is selected among the replacements as Tigers continue their quest for a place in the Guinness Premiership play-off places.
Leicester Tigers (v Bath away, Tuesday 8pm)
15 Sam Vesty
14 Tom Varndell
13 Ayoola Erinle
12 Matt Cornwell
11 Ollie Dodge
10 Ian Humphreys
9 Christophe Laussucq
1 Marcos Ayerza
2 Benjamin Kayser
3 Julian White
4 Richard Blaze
5 Ben Kay (c)
6 Tom Croft
7 Ben Pienaar
8 Brett Deacon
Replacements
16 Mefin Davies
17 Alex Moreno
18 Martin Corry
19 Jordan Crane
20 Frank Murphy
21 Aaron Mauger
22 Johne Murphy
