Elliot Daly (3), Alex Gray (2), Christian Wade, Rob Buchanan and Mako Vunipola claied the tries with Leicester Tigers fly-half Ford adding 16 points with the boot.
Ford’s club colleague Matt Everard gained another Under-20 cap as a replacement from Matt Kvesic in the back row, while Scotland included Tigers Academy player Hamish Watson at openside.
England now head into Friday’s match against Ireland in Athlone with the target of gaining the win which would secure a cleansweep for the first time since 2008.
England U20 team v Scotland:
15 Ben Ransom (Saracens)
14 Andy Short (Worcester Warriors)
13 Elliot Daly (London Wasps)
12 Owen Farrell (Saracens)
11 Christian Wade (London Wasps)
10 George Ford (Leicester Tigers)
9 Dan Robson (Gloucester Rugby)
1 Mako Vunipola (Bristol Rugby)
2 Rob Buchanan (Harlequins)
3 Will Collier (Harlequins)
4 Joe Launchbury (London Wasps)
5 Charlie Matthews (Harlequins)
6 Kieran Low (Harlequins)
7 Matt Kvesic (Worcester Warriors)
8 Alex Gray (C) (Newcastle Falcons)
Replacements:
16 Koree Britton (Gloucester Rugby) on for Rob Buchanan 55 mins
17 Henry Thomas (Sale Sharks) on for Will Collier 50 mins
18 Sam Jones (London Wasps) on for Keiran Low 48 mins
19 Matt Everard (Leicester Tigers) on for Matt Kvesic 74 mins
20 Chris Cook (Bath Rugby) on for Dan Robson 60 mins
21 Jamie Elliott (Northampton Saints) on for Ben Ransom 70 mins
22 Jonathan Joseph (London Irish) on for Andy Short 50 mins