Book your place now for the encounter between the defending English champions and the team that Tigers pipped to the title last season with a 10-9 victory in the Guinness Premiership Final at Twickenham.
As well as the clash with high-flying Irish, Tigers also have home games against old rivals Bath, Harlequins and Saracens to come.
Bath Rugby are the visitors to Welford Road on Easter Saturday, April 3 (3pm) so why not make a family day of it and enjoy a day at the home of the defending champions?
Harlequins head north on Saturday, April 24 (3pm) and the regular Guinness Premiership season concludes with long-time league leaders Saracens coming to Welford Road on Saturday, May 8 (3pm).
Each season Tigers can boast the best attendances in the Guinness Premiership and this year the new-look stadium has attracted average league gates of more than 22,000.
With a 24,000 capacity, you are advised to book as quickly as possible to guarantee the best available places.
Phone the Tigers ticket hotline on 0844 856 1880, call in at the Welford Road ticket office or book online.
The ticket office is open 8.30am-5.00pm every day, with late-night opening until 8pm on Wednesdays. Special rates apply for Group Bookings.