Coach Pierre Berbizier has named Salvatore Perugini of Toulouse, who was suspended during the autumn internationals, and Gloucester's Carlos Nieto as his starting pair, with Castrogiovanni and Andrea Lo Cicero of L'Aquilla as back-up on the bench.
The starting XV includes three players based with Guinness Premiership clubs, plus four from Leicester's Heineken Cup quarter-final rivals Stade Francais.
Italy
15 R de Marigny (Calvisano)
14 D Dallan (Stade Francais)
13 G Canale (Clermont Auvergne)
12 Mirco Bergamasco (Stade Francais)
11 A Masi (Biarritz)
10 A Scanavacca (Calvisano)
9 P Griffen (Calvisano)
1 S Perugini (Toulouse)
2 F Ongaro (Saracens)
3 C Nieto (Gloucester)
4 S Dellape (Biarritz)
5 M Bortolami (Gloucester, capt)
6 J Sole (Viadana)
7 Mauro Bergamasco (Stade Francais)
8 S Parisse (Stade Francais)
Replacements
16 A Festuccia (Gran Parma)
17 A Lo Cicero (L'Aquilla)
18 M Castrogiovanni (Leicester Tigers)
19 R Mandelli (Gran Pama)
20 A Troncon (Clermont Auvergne)
21 R Pez (Bayonne)
22 K Robertson (Viadana)
