The screen will be installed thanks to a partnership with GE, an international corporation working on finding solutions in energy, health and home, transportation and finance active in 130 countries.
The screen, which will be housed at the Clubhouse End, replaces the existing electronic scoreboard and is due for delivery in the new year.
It is scheduled to be in operation for the first time at the Aviva Premiership match against Gloucester on Sunday, February 16.
As well as allowing supporters to see extensive live coverage of matches, the screen will incorporate news from the club and messages for supporters during matchdays plus scoreboard and time functions.
Leicester Tigers chief executive Simon Cohen said: “We know from feedback among supporters at the stadium and from our Supporters Forum gatherings that a big screen is seen as a top priority in enhancing the matchday experience at Welford Road.
“This is something we have been looking at fulfilling for a while. Now, thanks to the sponsorship of GE, we are looking to have the new screen installed for the second half of the season.
“GE have been very enthusiastic in their support of the club and we know the screen will be a welcome addition to our matchdays.”
