Leicester Tigers duo Ellis Genge and Ben Youngs have been included in the England squad for their final fixture of the 2020 Guinness Six Nations and upcoming Autumn Nations Cup in November and December.
George Ford was not considered for selection due to an Achilles injury but the Tigers fly-half will join up with the squad for reconditioning.
Uncapped front-rower Joe Heyes will return to the club after taking part in the national squad's recent training camps.
The Tigers squad will come together this week as the 2020/21 pre-season programme commences at Oval Park in preparation for the beginning of the 2020/21 Gallagher Premiership campaign on Saturday, November 21 at home to Gloucester Rugby.
Head coach Eddie Jones said: “We were obviously disappointed with the postponement of the Barbarians game but we moved to plan B, had a highly competitive training session instead of the match and now we are fully focused on the Italy game and the goal of winning the Six Nations.
“It was a tough squad to pick and I know there are a number of disappointed players that have just missed out. With nine players out injured, it does create some opportunities for the younger guys to show what they can do. We’re very happy with what we’ve seen in the mini-camps and the Barbarians training week, it’s been really competitive.”
Joe Cokanasiga (Bath Rugby, 9 caps)
Owen Farrell (Saracens, 83 caps)
George Furbank (Northampton Saints, 2 caps)
Willi Heinz (Gloucester Rugby, 13 caps) (withdrawn injured, replaced by Alex Mitchell of Northampton Saints)
Jonathan Joseph (Bath Rugby, 50 caps)
Ollie Lawrence (Worcester Warriors, uncapped)
Max Malins (Bristol Bears, uncapped)
Joe Marchant (Harlequins, 3 caps)
Jonny May (Gloucester Rugby, 56 caps)
Dan Robson (Wasps, 2 caps)
Henry Slade (Exeter Chiefs, 29 caps)
Ollie Thorley (Gloucester Rugby, uncapped)
Jacob Umaga (Wasps, uncapped)
Anthony Watson (Bath Rugby, 43 caps)
Ben Youngs (Leicester Tigers, 99 caps)
Tom Curry (Sale Sharks, 23 caps)
Tom Dunn (Bath Rugby, uncapped)
Ben Earl (Bristol Bears, 3 caps)
Charlie Ewels (Bath Rugby, 15 caps)
Ellis Genge (Leicester Tigers, 18 caps)
Jamie George (Saracens, 49 caps)
Jonny Hill (Exeter Chiefs, uncapped)
Ted Hill (Worcester Warriors, 1 cap)
Maro Itoje (Saracens, 38 caps)
Joe Launchbury (Wasps, 65 caps)
Lewis Ludlam (Northampton Saints, 8 caps)
Beno Obano (Bath Rugby, uncapped)
David Ribbans (Northampton Saints, uncapped)
Jack Singleton (Gloucester Rugby, 3 caps)
Kyle Sinckler (Bristol Bears, 35 caps)
Will Stuart (Bath Rugby, 3 caps)
Sam Underhill (Bath Rugby, 18 caps)
Billy Vunipola (Saracens, 51 caps)
Mako Vunipola (Saracens, 59 caps)
Harry Williams (Exeter Chiefs, 18 caps)
Jack Willis (Wasps, uncapped)
England will travel to Rome to face Italy in the final round of the delayed 2020 Guinness Six Nations on Saturday, October 31 (4.45pm GMT KO). The match is live on ITV.
England will then play four matches as part of the Autumn Nations Cup, returning to Twickenham Stadium for Quilter Internationals against Georgia (Saturday 14 November, 3pm KO) and Ireland (Saturday 21 November, 3pm KO).
They will then face Wales away (Saturday 28 November, 4pm KO) before a placing match at home to determine final position in the competition (Sunday 6 December, 2pm KO). All Autumn Nations Cup games will be live on Amazon Prime.