Leicester Tigers hooker Harry Thacker, scorer of two tries in the win over Wales, starts again in the front row, with clubmate Henry Purdy among the replacements.
Full back Aaron Morris, wing Nathan Earle, fly half Sam Olver, lock Jonny Hill and No8 James Chisholm all come into the side and will be captained by Maro Itoje who moves into the back row from lock.
Coach Nick Walshe said: “We enjoyed the win against Wales but focus is very much on preparing to play a well-drilled Italy side. There’s no doubt that they have improved over the past couple of seasons and we know that we’ll be in for a tough match.”
England Under-20s
15 Aaron Morris (Bedford Blues)
14 Howard Packman (Northampton Saints)
13 Nick Tompkins (Saracens)
12 Harry Sloan (Harlequins)
11 Nathan Earle (Saracens)
10 Sam Olver (Northampton Saints)
9 Henry Taylor (Loughborough University)
1 Danny Hobbs-Awoyemi (Northampton Saints)
2 Harry Thacker (Leicester Tigers)
3 Scott Wilson (Newcastle Falcons)
4 Tom Ellis (Bath Rugby)
5 Jonny Hill (Gloucester Rugby)
6 Maro Itoje (Saracens)(c)
7 Joel Conlon (Exeter Chiefs)
8 James Chisholm (Harlequins)
Replacements:
16 Tom Woolstencroft (Bath Rugby)
17 Alex Lundberg (London Wasps)
18 Paul Hill (Leeds Carnegie)
19 Ross Moriarty (Gloucester Rugby)
20 Hayden Thompson Stringer (Saracens)
21 Callum Braley (Bristol Rugby)
22 Billy Burns (Gloucester Rugby)
23 Henry Purdy (Leicester Tigers)