Tigers wing Murphy is selected among the replacements while his former Leicester teammate Ian Humphreys is named at fly-half.
A vacancy has been left at hooker pending the Ireland team announcement tomorrow.
Ireland 'A' (v Tonga, Friday, November 13, Ravenhill, 7.35pm)
15. Gavin Duffy (Galwegians/Connacht)
14. Shane Horgan (Boyne/Leinster) Captain
13. Darren Cave (Belfast Harlequins/Ulster)
12. Fergus McFadden (Old Belvedere/Leinster)
11. Andrew Trimble (Ballymena/Ulster)
10. Ian Humphreys (Ballymena/Ulster)
9. Peter Stringer (Shannon/Munster)
1. Brett Wilkinson (Galwegians/Connacht)
2. A.N. Other
3. Mike Ross (Clontarf/Leinster)
4. Devin Toner (Lansdowne/Leinster)
5. Donnacha Ryan (Shannon/Munster)
6. Sean O'Brien (Clontarf/Leinster)
7. Neil Best (Northampton Saints)
8. Chris Henry (Ballymena/Ulster)
Replacements
16. Denis Fogarty (Cork Constitution/Munster)
17. Bryan Young (Ballymena/Ulster)
18. Dan Tuohy (Ballymena/Ulster)
19. Kevin McLaughlin (UCD/Leinster)
20. Isaac Boss (Ballymena/Ulster)
21. Ian Keatley (Galwegians/Connacht)
22. Johne Murphy (Leicester Tigers)
