Victory in the Round 4 match would secure top spot in Pool 2 and give Tigers a place in the semi-finals of the cup competition for the first time since 2008.
Horacio Agulla, Anthony Allen and Jeremy Staunton return to the Tigers backline, and there are recalls for Marcos Ayerza, George Chuter, Julian White and Steve Mafi in the forward pack, plus Thomas Waldrom who has been released from England training this week.
Ben Woods, who led Tigers to victory at Harlequins in Round 3, will captain the team at Welford Road for the first time.
Craig Newby is included in the senior squad for the first time since leading the team in last season’s Aviva Premiership Final following his recovery from a knee injury, and fly-half Toby Flood is back in the matchday squad after a hamstring injury.
Director of rugby Richard Cockerill, who saw a young side win at Harlequins in Round 3 last weekend, is without four players on international duty with England and Martin Castrogiovanni is away with Italy. Billy Twelvetrees and Ed Slater are with England Saxons and George Ford is captaining the England Under-20s.
Visitors Newcastle can also still claim a semi-final place and enjoyed a 37-7 victory over Sale Sharks last week under new director of rugby Gary Gold. Falcons have announced the arrival of former Tigers captain and coach John Wells as part of their coaching team this week.
Saturday’s match is included in Tigers season tickets.
All other supporters can purchase tickets now from the Tigers ticket office. Phone 0844 856 1880, call in at Welford Road or book online. Or book match tickets at the Club Store in Market Street, Leicester.
Leicester Tigers (v Newcastle Falcons, LV= Cup, Welford Road, Saturday 3.00pm)
15 Niall Morris
14 Horacio Agulla
13 Matt Smith
12 Anthony Allen
11 Scott Hamilton
10 Jeremy Staunton
9 Sam Harrison
1 Marcos Ayerza
2 George Chuter
3 Julian White
4 George Skivington
5 Graham Kitchener
6 Steve Mafi
7 Ben Woods (c)
8 Thomas Waldrom
Replacements
16 Rob Hawkins
17 Logoviii Mulipola
18 Ryan Bower
19 Craig Newby
20 Julian Salvi
21 James Grindal
22 Toby Flood
23 Andy Forsyth
Newcastle Falcons beat Sale Sharks 37-7 in Round 3 last week and can still qualify for the semi-finals with a win this Saturday.
Newcastle Falcons: 15 Greg Goosen, 14 Ryan Shortland, 13 Corne Uys, 12 James Fitzpatrick, 11 Suka Hufanga, 10 Jimmy Gopperth, 9 Chris Pilgrim, 1 Jonny Golding, 2 Rob Vickers, 3 James Hall, 4 Adriaan Fondse, 5 Tim Swinson, 6 Ally Hogg, 7 Richard Mayhew, 8 Mark Wilson. Replacements: 16 Joe Graham, 17 Darren Fearn, 18 Ashley Wells, 19 Richard Boyle, 20 Taiasina Tu’ifua, 21 Will Chudley, 22 Jamie Helleur, 23 Joel Hodgson
