Tuilagi, on his 17th international appearance, was joined in the England team by Tigers team-mates Dan Cole, Geoff Parling, Ben Youngs and Tom Youngs.
And he was instrumental in all three of England’s tries as they recorded their largest ever victory against the All Blacks.
The Tigers Academy graduate played a huge part in Brad Barritt’s first Test try on 54 minutes, exchanging passes with the Saracens centre before he crashed over.
Tuilagi’s break from midfield created the second moments later, his final pass giving Chris Ashton a run to the line.
And he scored one of his own on 62 minutes, intercepting Kieran Read’s pass and running in unopposed.
Owen Farrell had kicked England into a 15-0 lead before the All Blacks hit back after the break with quick-fire tries from Julian Savea and Read.
But England steadied the ship with their own three-try salvo, plus two late penalties for Freddie Burns on his debut. Savea added a try late on for the All Blacks but it was England’s day.