With Ben Kay ruled out by injury, skipper Corry starts in the second row, while England Elite Squad members Hipkiss, Croft and Crane are back in the starting XV after being rested last weekend.
France international Benjamin Kayser comes into the front row, while Scott Hamilton moves to full-back in the absence of the injured Geordan Murphy.
Martin Castrogiovanni and Ben Herring are again included among the replacements after their return from injury in the win over Newcastle Falcons last weekend.
Saturday’s game will be played in front of a sell-out 50,000 crowd, establishing a record for a single Guinness Premiership fixture. No tickets will be available on the day.
Leicester Tigers (v Harlequins, Twickenham Stadium, Saturday 4pm)
15 Scott Hamilton
14 Johne Murphy
13 Dan Hipkiss
12 Aaron Mauger
11 Matt Smith
10 Toby Flood
9 Julien Dupuy
1 Boris Stankovich
2 Benjamin Kayser
3 Julian White
4 Martin Corry (captain)
5 Marco Wentzel
6 Tom Croft
7 Lewis Moody
8 Jordan Crane
Replacements
16 George Chuter
17 Martin Castrogiovanni
18 Craig Newby
19 Ben Herring
20 Ben Youngs
21 Seru Rabeni
22 Tom Varndell
