Leicester Tigers back-rower Luke Hamilton will make his first start for Scotland when they take on USA in Houston on Sunday (kick-off 2am BST).
Hamilton will win his third international cap at openside flanker after appearances from the bench against New Zealand in the autumn and last weekend against Canada.
Leicester-bound David Denton, who was man-of-the-match in Scotland’s 48-10 win against Canada, is named among the back-row replacements.
They are set to face Chris Baumann after the Tigers prop was named on the bench by USA, who are again captained by former Tigers winger Blaine Scully.
Valentino Mapapalangi is also a back-row replacement for Tonga in their Pacific Nations Cup clash with Samoa. Logovi’i Mulipola has been ruled out of the game in Fiji through injury. The game kicks off at 2am on Saturday BST.
Scotland: 15 Stuart Hogg (c) (Glasgow Warriors, 60 caps), 14 Blair Kinghorn (Edinburgh, 3 caps), 13 Nick Grigg (Glasgow Warriors, caps), 12 Pete Horne (Glasgow Warriors, 33 caps), 11 Byron McGuigan (Sale Sharks, 4 caps), 10 Adam Hastings (Glasgow Warriors, 1 cap), 9 George Horne (Glasgow Warriors, uncapped); 1 Jamie Bhatti (Glasgow Warriors, 9 caps) , 2 George Turner (Glasgow Warriors, 3 caps), 3 Zander Fagerson (Glasgow Warriors, 16 caps), 4 Lewis Carmichael (Edinburgh, 1 cap), 5 Ben Toolis (Edinburgh, 10 caps), 6 Tim Swinson (Glasgow Warriors, 36 caps), 7 Luke Hamilton (Leicester Tigers, 2 caps), 8 Matt Fagerson (Glasgow Warriors, uncapped).
Replacements: 16 Fraser Brown (Glasgow Warriors, 32 caps), 17 Allan Dell (Edinburgh, 11 caps), 18 Murray McCallum (Edinburgh, 2 caps), 19 Grant Gilchrist (Edinburgh, 23 caps), 20 David Denton (Worcester Warriors, 40 caps), 21 Sam Hidalgo-Clyne (Scarlets, 10 caps), 22 Mark Bennett (Edinburgh, 21 caps), 23 Dougie Fife (Edinburgh, 6 caps)
USA: 15 Will Hooley (Bedford Blues), 14 Blaine Scully (c) (Cardiff Blues), 13 Bryce Campbell (Glendale Raptors), 12 Paul Lasike (Utah Warriors), 11 Marcel Brache (Western Force), 10 AJ MacGinty (Sale Sharks), 9 Shaun Davies (Glendale Raptors); 8 Cam Dolan (San Diego Legion), 7 Hanco Germishuys (Austin Elite), 6 John Quill (Glendale Raptors), 5 Nick Civetta (Newcastle Falcons), 4 Samu Manoa (Toulon), 3 Paul Mullen (Houston SaberCats), 2 Joe Taufete'e (Worcester Warriors), 1 Eric Fry (Vannes Rugby)
Replacements: 16 Dylan Fawsitt (Glendale Raptors), 17 Titi Lamositele (Saracens), 18 Chris Baumann (Leicester Tigers), 19 Greg Peterson (Glasgow Warriors), 20 Ben Landry (Glendale Raptors), 21 Nate Augspurger (San Diego Legion), 22 Will Magie (Glendale Raptors), 23 Dylan Audsley (San Diego Legion)
Tonga: 15 David Halaifonua, 14 Viliami Lolohea, 13 Nafi Tu'itavake, 12 Siale Piutau (c), 11 Cooper Vuna, 10 Kurt Morath, 9 Sonatane Takulua; 1 Siegfried Fisi'ihoi, 2 Paulo Ngauamo, 3 Siua Halanukonuka, 4 Leva Fifita, 5 Joe Tu'ineau, 6 Sitiveni Mafi, 7 Fotu Lokotui, 8 Nasi Manu
Replacements: 16 Sefo Sakalia, 17 David Feao, 18 Ben Tameifuna, 19 Valentino Mapapalangi, 20 Maama Vaipulu, 21 Suke Tuumotooa, 22 Latiume Fosita 23 Fifita