May starts on the wing, with Youngs at scrum-half, while Ford is named among the replacements in the second Quilter International Test of the autumn.
Jones makes three changes to the starting XV that beat South Africa 12-11 last weekend with Chris Ashton named to start on the right wing, Ben Moon at loosehead prop and Sam Underhill comes in at openside flanker following an ankle injury to Tom Curry.
There are three changes to the bench with Alec Hepburn, Courtney Lawes and Jack Nowell all included.
Jones said: “The expectation for Saturday is no different to any other Test match. We want to be at our best, better than we were in the previous Test match and we want to play with pride and passion which ignites the fan.
“It’s been a good week, the players have recovered well, trained well on Tuesday, exceptionally well on Wednesday, and we look forward to the challenge of taking on New Zealand on Saturday.”
There is live coverage of the game on Sky Sports.
Supporters can watch the game at Welford Road, with big screen coverage in Final Whistle. Tigers flanker Brendon O'Connor will provide his insight on the game and there is a pie-and-point food included in the ticket price of £10. Book now at the ticket office, phone 0116 319 8888 or online.
15 Elliot Daly (Wasps, 22 caps)
14 Chris Ashton (Sale Sharks, 40 caps)
13 Henry Slade (Exeter Chiefs, 14 caps)
12 Ben Te’o (Worcester Warriors, 14 caps)
11 Jonny May (Leicester Tigers, 38 caps)
10 Owen Farrell (Saracens, 62 caps) co-captain
9 Ben Youngs (Leicester Tigers, 78 caps)
1 Ben Moon (Exeter Chiefs, 1 cap)
2 Dylan Hartley (Northampton Saints, 94 caps) co-captain
3 Kyle Sinckler (Harlequins, 14 caps)
4 Maro Itoje (Saracens, 23 caps)
5 George Kruis (Saracens, 26 caps)
6 Brad Shields (Wasps, 3 caps)
7 Sam Underhill (Bath Rugby, 6 caps)
8 Mark Wilson (Newcastle Falcons, 5 caps)
16 Jamie George (Saracens, 29 caps)
17 Alec Hepburn (Exeter Chiefs, 3 caps)
18 Harry Williams (Exeter Chiefs, 12 caps)
19 Charlie Ewels (Bath Rugby, 7 caps)
20 Courtney Lawes (Northampton Saints, 65 caps)
21 Danny Care (Harlequins, 82 caps)
22 George Ford (Leicester Tigers, 48 caps)
23 Jack Nowell (Exeter Chiefs, 27 caps)