The 27-year-old is joined in the tour party by Tigers forwards Julian White, George Chuter, Tom Croft, Louis Deacon, Ben Kay, Lewis Moody and Jordan Crane, plus centre Dan Hipkiss, who have more than 200 senior international caps between them.
White will be hoping to earn his 50th England cap this summer, while Deacon, Kay, Moody, Crane and Hipkiss all celebrate their return to the international fold.
Vesty has been capped at England Saxons level but this is his first call into the senior set-up.
“It is a dream come true to get an England call,” said Vesty who picked up the Tigers Players’ Player of the Season award.
“I am just thankful to Richard Cockerill for giving me a chance in the Leicester team during the Six Nations period earlier this season. I’ve tried my hardest to play well each week and the England management must feel that I have done that.”
England side face the Barbarians – who include Tigers duo Martin Corry and Geordan Murphy in their squad – at Twickenham on May 30 before Tests against Argentina at Old Trafford on June 6 and then in South America on June 13.
England team manager Martin Johnson said "This is a very strong squad full of a mixture of experience and young talent. I'm sure that any of the uncapped players will take the step up from the Saxons to the senior test arena if they are given the opportunity.”
The 26-man England Saxons squad includes Tigers trio Dan Cole, Ben Woods and Tom Varndell in preparation for the Churchill Cup defence in Denver, Colorado.
ENGLAND SUMMER TOUR SQUAD
FORWARDS
Steffon Armitage (London Irish)
Steve Borthwick (Saracens, captain)
George Chuter (Leicester Tigers)
Jordan Crane (Leicester Tigers)
Tom Croft (Leicester Tigers)
Louis Deacon (Leicester Tigers)
Nick Easter (Harlequins)
Dylan Hartley (Northampton Saints)
James Haskell (London Wasps)
Ben Kay (Leicester Tigers)
Nick Kennedy (London Irish)
Lewis Moody (Leicester Tigers)
Tim Payne (London Wasps)
Tom Rees (London Wasps)
*Chris Robshaw (Harlequins)
Steve Thompson (CA Brive)
Julian White (Leicester Tigers)
*David Wilson (Newcastle Falcons)
*Nick Wood (Gloucester Rugby)
BACKS
Delon Armitage (London Irish)
Danny Care (Harlequins
Mark Cueto (Sale Sharks)
Ben Foden (Northampton Saints)
Andy Goode (CA Brive)
*Jordan Turner-Hall (Harlequins)
Dan Hipkiss (Leicester Tigers)
Paul Hodgson (London Irish)
*Tom May (Newcastle Falcons)
Olly Morgan (Gloucester Rugby)
Jamie Noon (Newcastle Falcons)
David Strettle (Harlequins)
Mathew Tait (Sale Sharks)
*Sam Vesty (Leicester Tigers)
Richard Wigglesworth (Sale Sharks)
*Denotes uncapped player
ENGLAND SAXONS CHURCHILL CUP SQUAD
FORWARDS
Dan Cole (Leicester Tigers)
Alex Corbiserio (London Irish)
Phil Dowson (Newcastle Falcons)
*David Flatman (Bath Rugby)
Tom Guest (Harlequins)
Stuart Hooper (Bath Rugby)
*Chris Jones (Sale Sharks)
Tom Mercey (Saracens)
*Luke Narraway (Gloucester Rugby)
*Dean Schofield (Sale Sharks)
Peter Short (Bath Rugby)
Joe Ward (London Wasps)
Rob Webber (London Wasps)
Ben Woods (Leicester Tigers)
BACKS
*Nick Abendanon (Bath Rugby)
Matt Banahan (Bath Rugby)
Brad Barritt (Saracens)
Noah Cato (Saracens)
*Danny Cipriani (London Wasps)
*Shane Geraghty (London Irish)
Alex Goode (Saracens)
Stephen Myler Northampton Saints)
Joe Simpson (London Wasps)
*Tom Varndell (Leicester Tigers)
Dominic Waldouck (London Wasps)
Micky Young (Newcastle Falcons)
* Denotes capped players
Tickets for England's match against the Barbarians on May 30 at Twickenham are available on a two for one special offer priced from £12.50 (offer ends midnight May 26) and are available by calling Ticketmaster on 0844 8472492 or by contacting www.ticketmaster.co.uk.
Tickets for Argentina v England for 'The Standard Bank Cup' at Old Trafford on June 6 are priced from just £10 for adults via Ticketmaster or by calling Manchester United via 0161 868 8000 (option 9).
