This is the first fixture with all players available following the end of the RBS 6 Nations and also the start of the six-game run-in to the end of the regular league season.
Tigers go into Round 16 in fourth place in the Aviva Premiership table, level on 49 points with third-placed Bath.
Chiefs are in action in the LV= Cup Final this weekend and will be hoping to maintain that momentum when they arrive at Welford Road.
With home crowds averaging around 22,000 this season, and just two more games on home turf after next week, tickets for this game are already in high demand. Book now for the best available places.
The Tigers ticket office is open 8.30am-5pm weekdays, until 8pm Wednesdays, and 9am-5pm Saturdays. Or book online any time.
Matchday hospitality packages are available for remaining home games. Phone the Corporate Sales team on 0116 2171 215 for details and to book your place.
Season tickets for 2014/15 are also on sale now, securing your place for every home game in the regular league season and pool fixtures in the cups as well as providing other benefits including priority booking for away games and any knockout matches, Tigers Store discounts every time you shop and the chance to buy international tickets. Click here for more details.