The six players, who began the pre-season programme under Steve Borthwick at Oval Park, are the first Tigers to agree a loan deal with Nottingham after the clubs announced the launch of a formal performance partnership.
Outside-back Browning also appeared for Nottingham during the 2020/21 season while on a short-term loan.
Hooker Vanes joins the Championship club on the back of featuring in England’s Under-20s Six Nations Grand Slam success.
Scrum-half Edwards co-captained the Tigers Academy to a third successive Under-18 League win in 2020 alongside Vanes.
Chessum, Cusick and Hoyt made the step up to senior rugby from the Academy programme ahead of the current season.
Speaking about the loan agreements, Tigers Head Coach Borthwick said: “This is a great opportunity for these young men to not only get valuable game time in the upcoming season but also exposure to senior rugby which is vital to their development.
“The partnership with Nottingham is something we are excited about at Leicester Tigers for its many elements, especially opportunities like this for our players to be a part of their programme.”
The Senior Academy members join senior squad players Sam Aspland-Robinson (Coventry Rugby) and Harry Simmons (Jersey Reds) on season-long loan agreements ahead of the new season.