Leicester Tigers will face-off while on loan this weekend in the Championship and National League One.
Scrum-half Sam Edwards is the lone Tigers player for Cambridge as they take on Nottingham, with props Archie Van Der Flier and Dan Richardson, lock Tom Manz and centre Joe Woodward all featuring.
In League one, hooker Finn Theobald-Thomas will play for Chinnor against Leicester Lions who have centre Charlie Myall and backrow Simon Koroiyadi in their ranks.
George Perkins will also be in action for Syston.