Ten members of the Leicester Tigers women's squad will feature in the opening round of WXV fixtures.
Amy Cokayne will come up against a quarter of her clubmates - Tahlia Brody, Tess Feury, Emily Henrich and Keia Mae Sagapolu Sanele - when England play the USA on Sunday at 8.30pm (UK time).
Late on Sunday evening, Canada - with Leicester Tigers duo Claire Gallagher and Julia Omokhuale - play France at 11.45pm (UK time).
In the WXV2 tournament opener, Catha Jacobs is on the South Africa bench for the match against Japan at 3.00pm (UK time) on Friday.
On Saturday, in WXC2, summer signing Abbey Constable is on the bench for Wales for their clash with Australia 11.30am (UK time) before Francesca McGhie starts for Scotland as their bid to retain the WXV2 title begins against Italy at 2.30pm (UK time).
Elsewhere, Claire Gallagher and Julia Omokhuale are set to be involved this Sunday as tournament hosts Canada face France (kick off: 11.45pm BST.
You can catch all WXV action live for free on RugbyPass.TV