Last season’s Guinness Premiership finalists, Tigers and Irish are again chasing places in the top four of the table with the season entering its last three months.
And with a break in the Six Nations this weekend, Tigers welcome back internationals Geordan Murphy, Toby Flood and Martin Castrogiovanni, while Tom Croft returns to the squad after injury.
Kick-off is at 5.35pm and Final Whistle, public bars, refreshment kiosks and the turnstiles open at 3.35pm.
There is also plenty going on around the ground before and after the game.
Competition sponsors Guinness will bring the game to life for fans with live Sky Sports commentary. They will be distributing free radios to supporters which will broadcast commentary from kick-off to the final whistle.
And following the success of last season’s Guinness Premiership Festivals the interactive games are back, with the Guinness Power Pass and Rugby Reflex adding to the pre-game excitement.
At the beginning of the season the speed of the twelve club captain’s passes was measured on the Guinness Power Pass and Geordan Murphy registered 32.8mph.
To test yourself against Tigers captain Murphy head to the Guinness games outside the Caterpillar Stand for your chance to win a Guinness goodie bag.
Tigers are teaming up with ABF The Soldiers' Charity at the match to assist in their efforts to provide support for soldiers, former soldiers and their families in times of need.
Charity wristbands will be on sale around Welford Road and Tigers will make a donation to the fund via the club's Cashback Scheme. There will also be an appearance by the Leicestershire & Rutland County Pipe Band.
Copies of Ben Herring’s new children's book, Boris Baloo, will be available from a stall in Final Whistle in the Caterpillar Stand with proceeds going to the Matt Hampson Trust.
And Coral, the official gaming and betting partner of the Guinness Premiership, will hold a new matchday game, the Hi-Lo Challenge, on the pitch at half-time. Pick up your scratch card on the way into the ground to see if you are a winner.
Guarantee the best available seat now by phoning the ticket hotline on 0844 856 1880, clicking here to book online or call in at Welford Road.