Tom Varndell starts on the wing, Alex Moreno is named at tighthead prop and Leo Cullen comes into the second row, with Alesana Tuilagi, Julian White and Ben Kay named among the replacements after starting the win over London Wasps a week ago.
Sam Vesty and Dan Hipkiss continue their partnership in the centres, with Harry Ellis and Andy Goode selected at half-back.
Varndell is joined by Irishman Geordan Murphy and Fijian Seru Rabeni in the back three, while Moreno props down alongside George Chuter and Marcos Ayerza.
Leo Cullen takes his place next to Louis Deacon in the second row, with flankers Shane Jennings and Lewis Moody either side of captain Martin Corry in the back row.
Tigers go into the game on the back of one defeat in their last eight outings, with their only reverse coming at the hands of Saturday's opponents in a re-arranged league fixture just under a fortnight ago.
Ticket sales
Tickets for Saturday's game are available from the Tigers ticket office.
Discounted prices for season ticket holders and members are available until close of play on Friday May 4. All tickets purchased on matchday will be at full price.
How to buy
Tickets can be purchased by calling 08701 28 34 30, visiting the Tigers ticket office or by booking online at http://www.tigers.talentarena.co.uk/ (NB Tickets booked online will not be eligible for discount.)
Ticket office opening hours
The ticket office will be open until 7pm on Friday, May 4 and from 9am on Saturday, May 5.
Leicester Tigers (vs Bristol Rugby, Welford Road, Saturday 5.30pm)
15 Geordan Murphy
14 Seru Rabeni
13 Dan Hipkiss
12 Sam Vesty
11 Tom Varndell
10 Andy Goode
9 Harry Ellis
1 Marcos Ayerza
2 George Chuter
3 Alex Moreno
4 Louis Deacon
5 Leo Cullen
6 Lewis Moody
7 Shane Jennings
8 Martin Corry (c)
Replacements
16 James Buckland
17 Julian White
18 Ben Kay
19 Brett Deacon
20 Frank Murphy
21 Ollie Smith
22 Alesana Tuilagi
